Ilgalaikiu stebimuoju kohortiniu tyrimu siekta patikrinti hipotez\u0119, kad \u017emon\u0117s, sergan\u00adtys permanentiniu prie\u0161ird\u017ei\u0173 virp\u0117jimu, ta\u00ad\u010diau nepatyr\u0119 galvos smegen\u0173 infarkto, pati\u00adria didesn\u012f kognityvini\u0173 funkcij\u0173 blog\u0117jim\u0105, palyginti su neturin\u010diaisiais ritmo sutrikimo. Ilgalaikiame analitiniame stebimajame (ko\u00adhortiniame) tyrime tirti 5 888 ligoniai, vyrai ir moterys per 65 metus, dalyvav\u0119 kardiovasku\u00adlin\u0117s sveikatos tyrime. Pradiniu tyrimo laiko\u00adtarpiu \u0161iems ligoniams nebuvo diagnozuotas nei prie\u0161ird\u017ei\u0173 virp\u0117jimas, nei galvos smegen\u0173 infarktas. Tiriamieji buvo \u0161alinami i\u0161 tyrimo, jeigu jiems \u012fvykdavo galvos smegen\u0173 infark\u00adtas. Prie\u0161ird\u017ei\u0173 virp\u0117jimo diagnoz\u0117 patvirtina\u00adma remiantis ligonin\u0117s i\u0161ra\u0161ais ir elektrokar\u00addiogramos (EKG) duomenimis. Tiriamiesiems kas metai buvo atliekamas sutrumpintas proti\u00adn\u0117s b\u016bkl\u0117s tyrimas (MMSE), stebima bendro bal\u0173 \u012fver\u010dio dinamika.<\/p>\n
Tyrime analizuoti 5 150 pacient\u0173 duomenys, i\u0161 j\u0173 552 (10,7 proc.) per 7 steb\u0117jimo metus i\u0161si\u00advyst\u0117 prie\u0161ird\u017ei\u0173 virp\u0117jimas. Ligoniai, kuriems tyrime nepasirei\u0161k\u0117 ritmo sutrikim\u0173, vidutini\u0161kai 3 balais geriau atlikdavo kognityvinio testo u\u017e\u00adduotis. Pavyzd\u017eiui, ligoni\u0173 tarp 80 ir 85 met\u0173, ne\u00adsergan\u010di\u0173 prie\u0161ird\u017ei\u0173 virp\u0117jimu, MMSE vidutinis \u012fvertis suma\u017e\u0117jo 6,4 balo per 5 metus, o to paties am\u017eiaus ligoni\u0173, sergan\u010di\u0173 patvirtintu prie\u0161ird\u017ei\u0173 virp\u0117jimu 5 metus, MMSE suma\u017e\u0117jo 10,3 balo. Skirtumas tarp \u0161i\u0173 grupi\u0173 buvo 3,9 balo (95 proc. PI nuo \u22125,3 iki \u22122,5).<\/p>\n
Tyrimo autoriai daro i\u0161vad\u0105, kad ligoniai, ser\u00adgantys prie\u0161ird\u017ei\u0173 virp\u0117jimu ir nepatyr\u0119 galvos smegen\u0173 infarkto, patiria greitesn\u012f kognityvini\u0173 funkcij\u0173 blog\u0117jim\u0105 nei ligoniai, neturintys ritmo sutrikim\u0173. Manoma, kad tai susij\u0119 su nedideliais lak\u016bniniais galvos smegen\u0173 infarktais, nepasi\u00adrei\u0161kian\u010diais klinikiniais simptomais, kuri\u0173 nu\u00adstatoma ma\u017edaug 25 proc. ligoni\u0173, sergan\u010di\u0173 l\u0117\u00adtiniu prie\u0161ird\u017ei\u0173 virp\u0117jimu, atlikus galvos smege\u00adn\u0173 MRT tyrim\u0105.<\/p>\n
Pareng\u0117 Giedr\u0117 Kri\u0161topaityt\u0117 <\/em><\/p>\n LITERAT\u016aRA<\/p>\n Thacker E.L., McKnight B., Psaty B.M. et al. Atrial fibrillation and cognitive decline: A longitudinal cohort study. Neurology<\/em>, 2013, Jul 9, 81 (2), 119\u2013125.<\/p>\n \u017durnalas \u201eInternistas\u201c<\/p>\n","protected":false},"excerpt":{"rendered":" Ilgalaikiu stebimuoju kohortiniu tyrimu siekta patikrinti hipotez\u0119, kad \u017emon\u0117s, sergan\u00adtys permanentiniu prie\u0161ird\u017ei\u0173 virp\u0117jimu, ta\u00ad\u010diau nepatyr\u0119 galvos smegen\u0173 infarkto, pati\u00adria didesn\u012f kognityvini\u0173 funkcij\u0173 blog\u0117jim\u0105, palyginti su neturin\u010diaisiais ritmo sutrikimo. Ilgalaikiame analitiniame stebimajame (ko\u00adhortiniame) tyrime tirti 5 888 ligoniai, vyrai ir moterys per 65 metus, dalyvav\u0119 kardiovasku\u00adlin\u0117s sveikatos tyrime. Pradiniu tyrimo laiko\u00adtarpiu \u0161iems ligoniams nebuvo diagnozuotas nei prie\u0161ird\u017ei\u0173 virp\u0117jimas, nei galvos smegen\u0173 infarktas. Tiriamieji buvo \u0161alinami i\u0161 tyrimo, jeigu jiems \u012fvykdavo galvos smegen\u0173 infark\u00adtas. Prie\u0161ird\u017ei\u0173 virp\u0117jimo diagnoz\u0117 patvirtina\u00adma remiantis ligonin\u0117s i\u0161ra\u0161ais ir elektrokar\u00addiogramos (EKG) duomenimis. Tiriamiesiems kas metai buvo atliekamas sutrumpintas proti\u00adn\u0117s b\u016bkl\u0117s tyrimas (MMSE), stebima bendro bal\u0173 \u012fver\u010dio dinamika.<\/p>\n","protected":false},"author":1,"featured_media":7975,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[27313],"tags":[93],"site":[],"post_item_type":[27345],"class_list":["post-7974","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-gydymo-naujienos","tag-infarktas"],"acf":{"post_sites":false},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.pasveik.lt\/lt\/wp-json\/wp\/v2\/posts\/7974","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pasveik.lt\/lt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pasveik.lt\/lt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pasveik.lt\/lt\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pasveik.lt\/lt\/wp-json\/wp\/v2\/comments?post=7974"}],"version-history":[{"count":0,"href":"https:\/\/www.pasveik.lt\/lt\/wp-json\/wp\/v2\/posts\/7974\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.pasveik.lt\/lt\/wp-json\/wp\/v2\/media\/7975"}],"wp:attachment":[{"href":"https:\/\/www.pasveik.lt\/lt\/wp-json\/wp\/v2\/media?parent=7974"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pasveik.lt\/lt\/wp-json\/wp\/v2\/categories?post=7974"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pasveik.lt\/lt\/wp-json\/wp\/v2\/tags?post=7974"},{"taxonomy":"site","embeddable":true,"href":"https:\/\/www.pasveik.lt\/lt\/wp-json\/wp\/v2\/site?post=7974"},{"taxonomy":"post_item_type","embeddable":true,"href":"https:\/\/www.pasveik.lt\/lt\/wp-json\/wp\/v2\/post_item_type?post=7974"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}